This thesis investigates safety and measurement methodology for Artisan iris-fixated phakic intraocular lenses in refractive surgery. It evaluates long-term clinical outcomes and examines how imaging modality and protocol affect key safety metrics in anterior segment assessment. The findings show that modality-dependent measurement variability can influence risk interpretation and follow-up decisions. The work contributes evidence-based recommendations to improve safety evaluation standards and longitudinal monitoring after pIOL implantation.