Dr. Jan-Willem M. Beenakker

Associate professor
Leiden University Medical Center
Depts. of Ophthalmology, Radiology and Radiation Oncology
Website: mreye.nl
E-mail: [email protected]

Addresses

Visiting address:
Leiden University Medical Center
C.J. Gorter MRI Center (route XXX)
Albinusdreef 2A
Leiden, The Netherlands

Mailing address:
Leiden University Medical Center
t.a.v. Dr. JWM Beenakker
postzone: J3-S
Postbus 9600
2300RC Leiden, The Netherlands

Born in Leiden (1984),
married and father of four children

Mission statement

I am a physicist by training who has made the transition from the fundamental research setting of a physics laboratory to the clinical setting of a medical hospital. Using my background in experimental physics, I develop novel technologies to enable MRI for ocular conditions and apply them clinically. My innovations have become part of regular clinical care, saving the vision and eyes of many patients.

Currently, my research focuses on ocular oncology, such as MR-based ocular radiotherapy planning and non-invasive quantification of eye tumor perfusion. Additionally, my ambition is to develop methods to fuse optical and MR-imaging of the eye, enabling the next paradigm shift in the treatment planning and follow-up of intra-ocular tumors.

Education and appointments

• 2021 - present, Associate Professor, Leiden UMC,
  depts. of Ophthalmology, Radiology and Radiation Oncology
• 2015 , Principal Investigator, Leiden UMC,
  depts. of Ophthalmology and Radiology
• 2008 - 2012, PhD in Physics, Leiden Institute of Physics
  Title: Unravelling the collagen network of the arterial wall
  Promotor: Prof. dr. ir. T. H. Oosterkamp

Distinctions

• 2024: One of the three LUMC PhD Supervisors of the year
• 2022: Dutch Research Council (NWO) VIDI laureate
• 2021: C.J. Kok Prize for translational research on ocular MRI
• 2016: ESCRS clinical Research Award
• 2016: Best oncology MR-research award, ISMRM Singapore

Professional activities

Responsibilities

• 2024 - present: Member of the scientific board of the HollandPTC
• 2024 - present: member of the science committee of the Dutch Ophthalmologist’s Association (NOG)
• 2021 – present: Chair of Pathology and Oncology section of the European Vision and Eye Research Association (EVER)
• 2021 – present: Member of the Ocular Proton Therapy Committee of the PTCOG
• 2021 – present: Board member of European Vision and Eye Research Association (EVER)
• 2021: Jury member of NWO TTW Open Technology Program
• 2017 – present: Grant reviewer for various national and international organizations

Graduated PhD students

• K. R. Keene: Function and structure of the eye muscles in myasthenia gravis, 2023
• T. A. Gonçalves-Ferreira: MR Imaging of Uveal Melanoma and Orbit, 2023
• M. G. Jaarsma-Coes, MRI for planning and characterization of uveal melanoma patients treated with proton beam therapy, 2023
• G. A. van Rijn: Safety of the artisan iris-fixated phakic intraocular lens, 2022
• Z. S. Gaurisankar: Phakic intraocular lens implantation: a life-long patient journey, 2022
• List of current group members

Conference activities

• 2024: Co-organizer of the 2nd international symposium on Ocular Proton Therapy
• 2023: Chair of the ocular oncology session at the Asia Pacific Academy of Ophthalmology conference in Kuala Lumpur
• 2023: Chair of the Oncology and Pathology session at the 2023 EVER congress in Valencia
• 2023: Organizer of a Negative Dysphotopsia symposium at the 2023 EVER congress in Valencia
• 2022 and 2023: Chair of the oncology and pathology sessions of the European Vision and Eye Research conference in Valencia
• 2021: Co-organizer and imaging session chair of first international ocular proton therapy course
• 2020: Coordinator and co-chair of European Vision Institute symposium on “New technologies for outcome measures in uveal melanoma” (Basel)
• 2015: Chair the scientific session on MR hardware development at the 7th annual ISMRM Benelux in Gent (Belgium)

Personal activities

• Since 2005 various responsibilities in national and international committees of the Emmanuel Community, a Catholic association with over 12.000 members in 72 countries. I’m currently part of the Dutch national governance and a member of the international advisory council (since 2018, re-elected in 2021).
  Two examples of responsibilities that shaped my leadership and mentoring skills

  • I've set-up the Dutch version of the Zacchaeus Course, a programme which helps the participants discover how to achieve unity and coherence in their lives, between their Christian faith and their day to day actions.
  • I have been in charge of the national youth team for 2008-2012. Together with my wife, I was a mentor for the youth, guided the local youth teams and (co-)organized over ten journeys in- and outside of Europe (impression). After our service in the youth team, we were responsible for the community in the West of the Netherlands (until 2020).
• Since 2015 a board member of the Dutch chapter of Aid to the Church in Need, a charity with approximately 4-6 million Euro of donations annually.

Publications

Open Science

• ZOSPy, an API for OpticStudio enabling automatic analyses (2021 - present)
  https://github.com/MREYE-LUMC/ZOSPy
  Role: Main author, active maintainer
• Various eye-models and associated ray-tracing analyses (2021 - present)
  https://github.com/MREYE-LUMC/ZOSPy/tree/main/examples/
  Role: main author
• T2EPG, EGP-based T2 analysis for muscle MRI (2022)
  https://git.lumc.nl/neuroscience
  Role: Contributor
• VFPy, a digitizing toolbox for Humphrey Visual Field analyses (2021)
  https://github.com/MREYE-LUMC/VFPy
  Role: Main author
• Ocular MRI protocol (2021)
  https://www.mriclinicalcasemap.philips.com/global/case/264
  Role: Main author
• PyZDDE, a Python link to Zemax API (2018)
  https://github.com/xzos/PyZDDE
  Role: Contributor

General public

• 2024: Article in the Dutch Physics Magazine (NTVN) on the physics of developing ocular MRI

• 2024: Article/interview in Medisch Contact: “PAROS: innovatieve methode voor het corrigeren van oogfoto's”

• 2024: Interview in Resultaat, the annual magazine of the Dutch Research Council [Dutch]/[English]

• 2023: Lecture on MRI for uveal melanoma at the annual patient day of Stichting Melanoom

• 2022: Lecture on “Working as a physicist in a hospital” at the annual gathering of the Dutch physics high-school teachers.

• 2022: Educational lectures on the technical and clinical aspects MRI for ocular proton therapy

• 2020: Article on “MRI for uvea melanoma” in De Oogarts

• 2020: Podcast on Ocular MRI of the Oogvereniging

Invited lectures

• 2024: Imaging for ocular proton therapy; OCULAR symposium, Villigen (Switzerland)
• 2023: Optical Ray tracing for Negative Dysphotopsia; European Society for Vision and Eye Research; Valencia (Spain)
• 2023: MRI for ocular proton therapy; European Ocular Oncology Group; Berlin (Germany);
• 2023: MRI for ocular radiotherapy planning; Asia Pacific Ophthalmic Academy; Kuala Lumpur (Malaysia)
• 2022: MRI of the eye; Brighton university; Brighton (UK)
• 2022: Imaging in Uveal Melanoma; International Society for Ocular Oncology; Leiden
• 2022: How can MRI help to optimize the treatment for Uveal Melanoma; Bebig; Leiden
• 2022: Is MRI useful to diagnose intra-ocular tumours?; International Society for Ocular Oncology; Leiden
• 2022: MRI for ocular proton therapy planning; International Ocular Proton Therapy Committee; Online/Villigen (Switzerland)
• 2021: MRI for ocular oncology; Asia Pacific Vitreo-Retina Society; originally in Hong Kong but online due to COVID
• 2021: MRI for Uveal Melanoma; European Vision Institute; originally in Basel (Switzerland) but online due to COVID
• 2020: Development of MRI-based proton therapy planning, European Society Magnetic Resonance in Medicine and Biology; Barcelona (Spain)
• 2020: MRI for ophthalmic conditions; German ophthalmic society (DOG), Berlin (Germany)
• 2020: The role of MRI in the care for Uveal Melanoma, World of Ophthalmology; Kaapstad (South Africa)
• 2020: Quantitative MRI for Ocular Oncology, World of Ophthalmology; Kaapstad (South Africa)
• 2019: The vRESPOND study; European Society of Cataract and Refractive Surgeons Society; Paris (France)
• 2017: Clinical Evaluation of UHF MRI for Uveal Melanoma; Asia-Pacific Congress of Ophthalmology; Singapore
• 2015: High resolution imaging of the eye; Laboratoria de Optica; Murcia (Spain)
• 2015: Ocular MRI; International Society of Magnetic Resonance Imaging in Medicine; Toronto (Canada)

Scientific Publications

2024

1. Pors, Haasjes, Vught, Hoes, Luyten, Rijn, Vu, Rasch, Horeweg and Beenakker. Correction Method for Optical Scaling of Fundoscopy Images: Development, Validation, and First Implementation. Investigative Opthalmology & Visual Science (2024), doi: 10.1167/iovs.65.1.43 

2. Tang, Klaassen, Marinkovic, Vu, Luyten, Creutzberg, Ketelaars and Beenakker. Evaluation of MRI safety of Ru-106 Eye applicators. Ocular Oncology and Pathology (2024), doi: 10.1159/000542712 

3. Klaassen, Haasjes, Hol, Lopes, Spruijt, Steeg-Henzen, Vu, Bakker, Rasch, Verbist and Beenakker. Geometrical accuracy of magnetic resonance imaging for ocular proton therapy planning. Physics and Imaging in Radiation Oncology (2024), doi: 10.1016/j.phro.2024.100598 

4. Makhotkina, Nijkamp, Berendschot, Borne, Kruchten, Vught, Beenakker, Krijgh, Aslam, Pesudovs and Nuijts. Measuring quality of vision including negative dysphotopsia. Acta Ophthalmologica (2024), doi: 10.1111/aos.15762 

5. Haasjes, Vu and Beenakker. Patient‐specific mapping of fundus photographs to three‐dimensional ocular imaging. Medical Physics (2024), doi: 10.1002/mp.17576 

6. Hrbacek, Kacperek, Beenakker, Mortimer, Denker, Mazal, Shih, Dendale, Slopsema, Heufelder and Mishra. PTCOG Ocular Statement: Expert Summary of Current Practices and Future Developments in Ocular Proton Therapy. International Journal of Radiation OncologyBiologyPhysics (2024), doi: 10.1016/j.ijrobp.2024.06.017 

7. Klaassen, Jaarsma-Coes, Marinkovic, Luyten, Rasch, Ferreira and Beenakker. Quantitative Perfusion-Weighted Magnetic Resonance Imaging in Uveal Melanoma. Investigative Ophthalmology & Visual Science (2024), doi: 10.1167/iovs.65.11.17 

8. Vught, Haasjes and Beenakker. ZOSPy: optical ray tracing in Python through OpticStudio. Journal of Open Source Software (2024), doi: 10.21105/joss.05756 

2023

9. Jaarsma-Coes, Ferreira, Marinkovic, Vu, Vught, Haren, Rodrigues, Klaver, Verbist, Luyten, Rasch and Beenakker. Comparison of Magnetic Resonance Imaging–Based and Conventional Measurements for Proton Beam Therapy of Uveal Melanoma. Ophthalmology Retina (2023), doi: 10.1016/j.oret.2022.06.019 

10. Keene, Nie, Brink, Notting, Verschuuren, Kan, Beenakker and Tannemaat. Diagnosing myasthenia gravis using orthoptic measurements: assessing extraocular muscle fatiguability. Journal of Neurology, Neurosurgery & Psychiatry (2023), doi: 10.1136/jnnp-2022-329859 

11. Keene, Notting, Verschuuren, Voermans, Keizer, Beenakker, Tannemaat and Kan. Eye Muscle MRI in Myasthenia Gravis and Other Neuromuscular Disorders. Journal of Neuromuscular Diseases (2023), doi: 10.3233/jnd-230023 

12. Jaarsma-Coes, Klaassen, Verbist, Vu, Klaver, Rodrigues, Nabarro, Luyten, Rasch, Herk and Beenakker. Inter-Observer Variability in MR-Based Target Volume Delineation of Uveal Melanoma. Advances in Radiation Oncology (2023), doi: 10.1016/j.adro.2022.101149 

13. Jaarsma-Coes, Klaassen, Marinkovic, Luyten, Vu, Ferreira and Beenakker. Magnetic Resonance Imaging in the Clinical Care for Uveal Melanoma Patients—A Systematic Review from an Ophthalmic Perspective. Cancers (2023), doi: 10.3390/cancers15112995 

14. Grzybowski and Beenakker. More on light dysphotopsia origin in pseudophakia. Graefe's Archive for Clinical and Experimental Ophthalmology (2023), doi: 10.1007/s00417-023-06029-w 

15. Tang, Ferreira, Marinkovic, Jaarsma-Coes, Klaassen, Vu, Creutzberg, Rodrigues, Horeweg, Klaver, Rasch, Luyten and Beenakker. MR-based follow-up after brachytherapy and proton beam therapy in uveal melanoma. Neuroradiology (2023), doi: 10.1007/s00234-023-03166-1 

16. Vught, Luyten and Beenakker. Peripheral visual field shifts after intraocular lens implantation. Journal of Cataract & Refractive Surgery (2023), doi: 10.1097/j.jcrs.0000000000001299 

17. Tong, Bastiaannet, Speetjens, Blank, Luyten, Jager, Marinkovic, Vu, Rasch, Creutzberg, Beenakker, Hartgrink, Bosch, Kiliç, Naus, Yavuzyigitoglu, Rij, Burgmans and Kapiteijn. Time Trends in the Treatment and Survival of 5036 Uveal Melanoma Patients in The Netherlands over a 30-Year Period. Cancers (2023), doi: 10.3390/cancers15225419 

2022

18. Tang, Jaarsma‐Coes, Ferreira, Fonk, Marinkovic, Luyten and Beenakker. A Comparison of 3 T and 7 T MRI for the Clinical Evaluation of Uveal Melanoma. Journal of Magnetic Resonance Imaging (2022), doi: 10.1002/jmri.27939 

19. Klaassen, Jaarsma-Coes, Verbist, Vu, Marinkovic, Rasch, Luyten and Beenakker. Automatic Three-Dimensional Magnetic Resonance-based measurements of tumour prominence and basal diameter for treatment planning of uveal melanoma. Physics and Imaging in Radiation Oncology (2022), doi: 10.1016/j.phro.2022.11.001 

20. Keene, Kan, Meeren, Verbist, Tannemaat, Beenakker and Verschuuren. Clinical and imaging clues to the diagnosis and follow‐up of ptosis and ophthalmoparesis. Journal of Cachexia, Sarcopenia and Muscle (2022), doi: 10.1002/jcsm.13089 

21. Vught, Que, Luyten and Beenakker. Effect of anatomical differences and intraocular lens design on negative dysphotopsia. Journal of Cataract & Refractive Surgery (2022), doi: 10.1097/j.jcrs.0000000000001054 

22. Jaarsma-Coes, Ferreira, Houdt, Heide, Luyten and Beenakker. Eye-specific quantitative dynamic contrast-enhanced MRI analysis for patients with intraocular masses. Magnetic Resonance Materials in Physics, Biology and Medicine (2022), doi: 10.1007/s10334-021-00961-w 

23. Beenakker and Rasch. Letter to the Editor of Radiotherapy and Oncology regarding the paper titled “MRI and FUNDUS image fusion for improved ocular biometry in Ocular Proton Therapy” by Via et al.. Radiotherapy and Oncology (2022), doi: 10.1016/j.radonc.2022.08.018 

24. Islamaj, Vught, Jordaan-Kuip, Vermeer, Ferreira, Waard, Lemij and Beenakker. Magnetic resonance imaging reveals possible cause of diplopia after Baerveldt glaucoma implantation. PLoS ONE (2022), doi: 10.1371/journal.pone.0276527 

25. Ferreira, Jaarsma-Coes, Marinkovic, Verbist, Verdijk, Jager, Luyten and Beenakker. MR imaging characteristics of uveal melanoma with histopathological validation. Neuroradiology (2022), doi: 10.1007/s00234-021-02825-5 

26. Beenakker, Brouwer, Chau, Coupland, Fiorentzis, Heimann, Heufelder, Joussen, Kiilgaard, Kivelä, Piperno-Neumann, Rantala, Romanowska-Dixon, Shields, Willerding, Wheeler-Schilling, Scholl, Jager and Damato. Outcome Measures of New Technologies in Uveal Melanoma: Review from the European Vision Institute Special Interest Focus Group Meeting. Ophthalmic Research (2022), doi: 10.1159/000524372 

27. Rozendal, Vught, Luyten and Beenakker. The Value of Static Perimetry in the Diagnosis and Follow-up of Negative Dysphotopsia. Optometry and Vision Science (2022), doi: 10.1097/opx.0000000000001918 

28. Gaurisankar, Rijn, Cheng, Luyten and Beenakker. Two-year results after combined phacoemulsification and iris-fixated phakic intraocular lens removal. Graefe's Archive for Clinical and Experimental Ophthalmology (2022), doi: 10.1007/s00417-021-05442-3 

2021

29. Hassan, Fleury, Shamonin, Fonk, Marinkovic, Jaarsma-Coes, Luyten, Webb, Beenakker and Stoel. An Automatic Framework to Create Patient-specific Eye Models From 3D Magnetic Resonance Images for Treatment Selection in Patients With Uveal Melanoma. Advances in Radiation Oncology (2021), doi: 10.1016/j.adro.2021.100697 

30. Gaurisankar, Rijn, Luyten and Beenakker. Differences between Scheimpflug and optical coherence tomography in determining safety distances in eyes with an iris-fixating phakic intraocular lens. Graefe's Archive for Clinical and Experimental Ophthalmology (2021), doi: 10.1007/s00417-020-04874-7 

31. Vught, Dekker, Stoel, Luyten and Beenakker. Evaluation of intraocular lens position and retinal shape in negative dysphotopsia using high-resolution magnetic resonance imaging. Journal of Cataract & Refractive Surgery (2021), doi: 10.1097/j.jcrs.0000000000000576 

32. Rijn, Gaurisankar, Saxena, Gibbes, Jongman, Haasnoot, Cheng, Beenakker and Luyten. Implantation of an iris-fixated phakic intraocular lens for the correction of hyperopia: 15-year follow-up. Journal of Cataract & Refractive Surgery (2021), doi: 10.1097/j.jcrs.0000000000000532 

33. Gaurisankar, Rijn, Haasnoot, Verhoeven, Klaver, Luyten and Beenakker. Long‐term longitudinal changes in axial length in the Caucasian myopic and hyperopic population with a phakic intraocular lens. Acta Ophthalmologica (2021), doi: 10.1111/aos.14647 

34. Vught, Shamonin, Luyten, Stoel and Beenakker. MRI-based 3D retinal shape determination. BMJ Open Ophthalmology (2021), doi: 10.1136/bmjophth-2021-000855 

35. Niendorf, Beenakker, Langner, Erb-Eigner, Cuadra, Beller, Millward, Niendorf and Stachs. Ophthalmic Magnetic Resonance Imaging: Where Are We (Heading To)?. Current Eye Research (2021), doi: 10.1080/02713683.2021.1874021 

36. Vught, Beenakker and Luyten. Reply to comment on: Distinct differences in anterior chamber configuration and peripheral aberrations in negative dysphotop. Journal of Cataract and Refractive Surgery (2021), doi: 10.1097/j.jcrs.0000000000000431 

37. Velde, Hooijmans, Mishre, Keene, Koeks, Veeger, Alleman, Zwet, Beenakker, Verschuuren, Kan and Niks. Selection Approach to Identify the Optimal Biomarker Using Quantitative Muscle MRI and Functional Assessments in Becker Muscular Dystrophy. Neurology (2021), doi: 10.1212/wnl.0000000000012233 

38. Keene, Vught, Velde, Ciggaar, Notting, Genders, Verschuuren, Tannemaat, Kan and Beenakker. The feasibility of quantitative MRI of extra‐ocular muscles in myasthenia gravis and Graves' orbitopathy. NMR in Biomedicine (2021), doi: 10.1002/nbm.4407 

39. Fleury, Trnková, Erdal, Hassan, Stoel, Jaarma‐Coes, Luyten, Herault, Webb, Beenakker, Pignol and Hoogeman. Three‐dimensional MRI‐based treatment planning approach for non‐invasive ocular proton therapy. Medical Physics (2021), doi: 10.1002/mp.14665 

2020

40. Vught, Luyten and Beenakker. Distinct differences in anterior chamber configuration and peripheral aberrations in negative dysphotopsia. Journal of Cataract and Refractive Surgery (2020), doi: 10.1097/j.jcrs.0000000000000206 

41. Rijn, Wijnen, Dooren, Cheng, Beenakker and Luyten. Improved Interchangeability with Different Corneal Specular Microscopes for Quantitative Endothelial Cell Analysis. Clinical Ophthalmology (Auckland, N.Z.) (2020), doi: 10.2147/opth.s228347 

42. Jaarsma-Coes, Marinkovic, Astreinidou, Schuurmans, Peters, Luyten, Rasch and Beenakker. Measuring eye deformation between planning and proton beam therapy position using magnetic resonance imaging. Physics and Imaging in Radiation Oncology (2020), doi: 10.1016/j.phro.2020.09.010 

43. Rijn, Gaurisankar, Ilgenfritz, Lima, Haasnoot, Beenakker, Cheng and Luyten. Middle- and long-term results after iris-fixated phakic intraocular lens implantation in myopic and hyperopic patients: a meta-analysis. Journal of Cataract and Refractive Surgery (2020), doi: 10.1097/j.jcrs.0000000000000002 

44. Ferreira, Pinheiro, Saraiva, Jaarsma-Coes, Duinen, Genders, Marinkovic and Beenakker. MR and CT Imaging of the Normal Eyelid and its Application in Eyelid Tumors. Cancers (2020), doi: 10.3390/cancers12030658 

45. Keene, Beenakker, Hooijmans, Naarding, Niks, Otto, Pol, Tannemaat, Kan and Froeling. T2 relaxation‐time mapping in healthy and diseased skeletal muscle using extended phase graph algorithms. Magnetic Resonance in Medicine (2020), doi: 10.1002/mrm.28290 

46. Fonk, Ferreira, Webb, Luyten and Beenakker. The Economic Value of MR-Imaging for Uveal Melanoma. Clinical Ophthalmology (Auckland, N.Z.) (2020), doi: 10.2147/opth.s238405 

2019

47. Koolstra, Beenakker, Koken, Webb and Börnert. Cartesian MR fingerprinting in the eye at 7T using compressed sensing and matrix completion‐based reconstructions. Magnetic Resonance in Medicine (2019), doi: 10.1002/mrm.27594 

48. Gaurisankar, Rijn, Lima, Ilgenfritz, Cheng, Haasnoot, Luyten and Beenakker. Correlations between ocular biometrics and refractive error: A systematic review and meta‐analysis. Acta Ophthalmologica (2019), doi: 10.1111/aos.14208 

49. Jaarsma-Coes, Ferreira, Haren, Marinkovic and Beenakker. MRI enables accurate diagnosis and follow-up in uveal melanoma patients after vitrectomy. Melanoma Research (2019), doi: 10.1097/cmr.0000000000000568 

50. Ferreira, Fonk, Jaarsma-Coes, Haren, Marinkovic and Beenakker. MRI of Uveal Melanoma. Cancers (2019), doi: 10.3390/cancers11030377 

51. Jaarsma-Coes, Ferreira, Luyten and Beenakker. Reaction on “Ocular ultrasound versus MRI in the detection of extrascleral extension in a patient with choroidal melanoma”. BMC Ophthalmology (2019), doi: 10.1186/s12886-019-1206-y 

52. Beenakker, Wezel, Groen, Webb and Börnert. Silent volumetric multi-contrast 7 Tesla MRI of ocular tumors using Zero Echo Time imaging. PLoS ONE (2019), doi: 10.1371/journal.pone.0222573 

2018

53. Jong, Graaf, Pouwels, Beenakker, Jansen, Geurts, Moll, Castelijns, Valk and Weerd. 9.4T and 17.6T MRI of Retinoblastoma: Ex Vivo evaluation of microstructural anatomy and disease extent compared with histopathology. Journal of Magnetic Resonance Imaging (2018), doi: 10.1002/jmri.25913 

54. Ferreira, Saraiva, Genders, Buchem, Luyten and Beenakker. CT and MR imaging of orbital inflammation. Neuroradiology (2018), doi: 10.1007/s00234-018-2103-4 

2017

55. Wezel, Garpebring, Webb, Osch and Beenakker. Automated eye blink detection and correction method for clinical MR eye imaging. Magnetic Resonance in Medicine (2017), doi: 10.1002/mrm.26355 

56. Isakova, Pralits, Romano, Beenakker, Shamonin and Repetto. Equilibrium shape of the aqueous humor-vitreous substitute interface in vitrectomized eyes. Journal for Modeling in Ophthalmology (2017), doi: 10.35119/maio.v1i3.36 

57. Diemen, Berends, Akram, Wezel, Teeuwisse, Mik, Kan, Webb, Beenakker and Groeneveld. Validation of a pharmacological model for mitochondrial dysfunction in healthy subjects using simvastatin: A randomized placebo-controlled proof-of-pharmacology study. European Journal of Pharmacology (2017), doi: 10.1016/j.ejphar.2017.09.031 

2016

58. Beenakker, Ferreira, Soemarwoto, Genders, Teeuwisse, Webb and Luyten. Clinical evaluation of ultra-high-field MRI for three-dimensional visualisation of tumour size in uveal melanoma patients, with direct relevance to treatment planning. Magnetic Resonance Materials in Physics, Biology and Medicine (2016), doi: 10.1007/s10334-016-0529-4 

2015

59. Beenakker, Shamonin, Webb, Luyten and Stoel. Automated Retinal Topographic Maps Measured With Magnetic Resonance Imaging. Investigative Ophthalmology & Visual Science (2015), doi: 10.1167/iovs.14-15161 

2014

60. Ruytenberg, Webb and Beenakker. A multi-purpose open-source triggering platform for magnetic resonance. Journal of Magnetic Resonance (2014), doi: 10.1016/j.jmr.2014.08.009 

2013

61. Brand, Webb and Beenakker. Design and performance of a transformer‐coupled double resonant quadrature birdcage coil for localized proton and phosphorus spectroscopy in the human calf muscle at 7 T. Concepts in Magnetic Resonance Part A (2013), doi: 10.1002/cmr.a.21281

62. Beenakker, Rijn, Luyten and Webb. High‐resolution MRI of uveal melanoma using a microcoil phased array at 7 T. NMR in Biomedicine (2013), doi: 10.1002/nbm.3041 

2012

63. Beenakker, Ashcroft, Lindeman and Oosterkamp. Mechanical Properties of the Extracellular Matrix of the Aorta Studied by Enzymatic Treatments. Biophysical Journal (2012), doi: 10.1016/j.bpj.2012.03.041 

64. He, Lamers, Beenakker, Cui, Ghotra, Danen, Meijer, Spaink and Snaar‐Jagalska. Neutrophil‐mediated experimental metastasis is enhanced by VEGFR inhibition in a zebrafish xenograft model. The Journal of Pathology (2012), doi: 10.1002/path.4013 

2010

65. Lindeman, Ashcroft, Beenakker, Es, Koekkoek, Prins, Tielemans, Abdul-Hussien, Bank and Oosterkamp. Distinct defects in collagen microarchitecture underlie vessel-wall failure in advanced abdominal aneurysms and aneurysms in Marfan syndrome. Proceedings of the National Academy of Sciences (2010), doi: 10.1073/pnas.0910312107