MReye researchers testing ocular MRI equipment at Leiden UMC
Jan-Willem Beenakker, Principal Investigator of the MReye research group at Leiden UMC

Principal Investigator

Jan-Willem Beenakker [CV], professor of Ophthalmic Physics at Leiden University, is a physicist by training who has made the transition from the fundamental research setting of a physics laboratory to the clinical setting of a hospital. Using his background in experimental physics, he develops novel technologies to enable MRI for ocular conditions and applies them clinically. His innovations have become part of regular clinical care, saving the vision and eyes of many patients.

Current members

  • Jan-Willem Beenakker

    Jan-Willem Beenakker

    Professor

    Jan-Willem is a physicist who, after his PhD, started his research group in an academic hospital. Using his background in experimental physics, he develops novel technologies to enable MRI for ocular conditions and applies them clinically.

  • Corné Haasjes

    Corné Haasjes

    PhD candidate

    After obtaining his master’s degree in Medical Physics, Corné started his PhD as part of the COMPOSE project to develop techniques to accurately combine optical fundus imaging with MRI. He is one of the active maintainers of Visisipy.

  • Martijn Hol

    Martijn Hol

    PhD candidate

    Since 2015, Martijn has worked as a medical physics engineer specialized in image-guided radiotherapy. In 2023, he started a PhD on clipless ocular proton therapy together with HollandPTC, focusing on the uncertainties within the current workflow.

  • Lisa Klaassen

    Lisa Klaassen

    Postdoc

    After obtaining her master’s in Technical Medicine, Lisa started her scientific career aiming to improve ocular proton treatment planning with MRI. She combines research with patient care as a technical physician at HollandPTC.

  • Lennart Pors

    Lennart Pors

    PhD candidate

    After his training as a medical doctor, Lennart went on to pursue his PhD working on MRI-based eye modeling and radiotherapy treatment planning, including NTCP modeling of the eye’s healthy structures.

  • Iris Mulder

    Iris Mulder

    PhD candidate

    After obtaining her Master’s degree in Biomedical Engineering, track Medical Physics, Iris started her PhD as part of the COMPOSE project. She will work on accurately incorporating MR images in ocular radiotherapy planning.

  • Anna Noordermeer

    Anna Noordermeer

    RT Technician

    As a radiotherapy lab technician, Anna is specialized in treatment planning. In addition to her clinical duties, she assists in the development and evaluation of MRI-based ocular proton therapy planning.

  • Nadine van Dam

    Nadine van Dam

    PhD candidate

    Following the completion of her Master’s degree in Electrical Engineering, Nadine embarked on her PhD, dedicating her research to the development of an ocular cone-beam CT scanner for eye cancer patients.

  • Louise Albertyn

    Louise Albertyn

    PhD candidate

    After working as an ophthalmology resident not in training (ANIOS), Louise started her PhD as part of the PACT4eye project, contributing to the clinical development of a photo-activated chemotherapy for the treatment of uveal melanoma.

  • Guus Versteeg

    Guus Versteeg

    PhD candidate

    As a technical physician, Guus continued his career with a PhD in the Departments of Ophthalmology and Radiotherapy, where he works on the clinical implementation of an ocular cone‑beam CT scanner for eye cancer patients.

  • Tekin Kirbiz

    Tekin Kirbiz

    Master student

    Tekin is a medical master’s student with a focus on ophthalmology. His thesis research examines shifts in treatment selection for uveal melanoma since the introduction of ocular proton therapy in the Netherlands.

  • Marlene den Brok

    Marlene den Brok

    Master student

    Marlene is a Technical Medicine master’s student. In her thesis research, she will study the effect of linear energy transfer (LET) in treatment planning for ocular proton therapy.

  • Ayesti Bos

    Ayesti Bos

    Master student

    Ayesti is a master’s student in Biomedical Technology and Physics at Vrije Universiteit Amsterdam. Her research investigates which CT reconstruction technique best visualizes ocular tumors for radiotherapy planning.

  • Jeffrey Dijkstra

    Jeffrey Dijkstra

    Master student

    Jeffrey is a physics student with an interest in medical physics. For his research project, he uses microCT imaging to map the stopping power of eyes with uveal melanoma, with the aim of improving the accuracy of ocular proton therapy.

Collaborators

As members of the Leiden Ocular Tumour Center, we work closely with both clinicians and scientists. These collaborations allow us to achieve a swift translation from technical development to societal impact.

    Ophthalmology

    • Khanh Vu
    • Marina Marinkovic
    • Gré Luyten
    • Martine Jager
    • Noor Hoes

    Radiology

    • Teresa Ferreira
    • Berit Verbist
    • Guido van Haren
    • Thomas Ruytenberg
    • Arjon van Lange

    Radiation Oncology

    • Coen Rasch
    • Steven Habraken
    • Nanda Horeweg
    • Eleftheria Astreinidou

    Gorter MRI Center

    • Andrew Webb
    • Thijs van Osch
    • Hermien Kan
    • Louise van der Weerd

    HollandPTC

    • Pauline Bakker
    • Fasco van Ommen
    • Mischa Hoogeman
    • Christel v/d Steeg
    • Patricia Cambraia Lopes

    Others

    • Martijn Tannemaat and Jan Verschuren (LUMC dept. Neurology)
    • Just Herder (TU Delft)
    • Caroline Klaver (Erasmus MC)
    • PTCOG Ocular members

Alumni

NameWhat did they do next
Bas v/d Burgh (2023 - 2024)High-tech engineer at VIRO
Luc van Vught (2016 - 2022)Started an ophthalmology residency at the LUMC
Kevin Keene (2018 - 2022)Started as Neurology resident at Haga in The Hague
Teresa Ferreira (2015 - 2023)Senior neuroradiologist at LUMC
Myriam Jaarsma-Coes (2017 - 2021)Data scientist at Sint Jansdal in Harderwijk
Kilany Hassan (2017 - 2019)Postdoc at department of Radiotherapy LUMC
Niels Dekker (2016 - 2021)Scientific programmer at Leiden Center for Clinical Image Processing
Zoraida Gaurisankar (2014 - 2020)Ophthalmologist at OLVG in Amsterdam
Gwyneth van Rijn (2011 - 2020)Ophthalmologist at Amsterdam University Medical Center
Lorna Grech-Fonk (2016 - 2020)Ophthalmology physician assistant at Gelre Ziekenhuizen in Apeldoorn

Our alumni are part of a longer scientific tradition; the PhD family tree maps that lineage.